Robb, Graeme R.: search on Z-Library

The world's largest scientific articles store. 70,000,000+ articles for free.

1

Property based optimisation of glucokinase activators – discovery of the phase IIb clinical candidate AZD1656

Waring, Michael J., Clarke, David S., Fenwick, Mark D., Godfrey, Linda, Groombridge, Sam D., Johnstone, Craig, McKerrecher, Darren, Pike, Kurt G., Rayner, John W., Robb, Graeme R., Wilson, Ingrid

Journal:

Year:

2012

Language:

english

File:

PDF, 253 KB

english, 2012

2

Matched Molecular Pairs as a Medicinal Chemistry Tool

Griffen, Ed, Leach, Andrew G., Robb, Graeme R., Warner, Daniel J.

Journal:

Journal of Medicinal Chemistry

Year:

2011

Language:

english

File:

PDF, 2.77 MB

english, 2011

3

Optimization of Permeability in a Series of Pyrrolotriazine Inhibitors of IRAK4

Degorce, Sébastien L., Anjum, Rana, Dillman, Keith S., Drew, Lisa, Groombridge, Sam D., Halsall, Christopher T., Lenz, Eva M., Lindsay, Nicola A., Mayo, Michele F., Pink, Jennifer H., Robb, Graeme R.,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2018

Language:

english

File:

PDF, 1.49 MB

english, 2018

4

Hypothesis driven drug design: improving quality and effectiveness of the design-make-test-analyse cycle

Alleyn T. Plowright, Craig Johnstone, Jan Kihlberg, Jonas Pettersson, Graeme Robb, Richard A. Thompson

Journal:

Drug Discovery Today

Year:

2012

Language:

english

File:

PDF, 334 KB

english, 2012

5

Matched triplicate design sets in the optimisation of glucokinase activators – maximising medicinal chemistry information content

Waring, Michael J., Bennett, Stuart N. L., Boyd, Scott, Campbell, Leonie, Davies, Robert D. M., Gerhardt, Stefan, Hargreaves, David, Martin, Nathaniel G., Robb, Graeme R., Wilkinson, Gary

Journal:

Year:

2013

Language:

english

File:

PDF, 304 KB

english, 2013

6

Lactose malabsorption in Central Australian Aboriginal children hospitalized with acute enteritis

GRAEME R. EDGELEY, GEOFFREY P. DAVIDSON, DEBORAH A. GOODWIN, MARGARETE L. RINGENBERGS, JOHN ERLICH, TREVOR A. ROBB

Journal:

Journal of Gastroenterology and Hepatology

Year:

1988

Language:

english

File:

PDF, 436 KB

english, 1988

7

Optimization of Brain Penetrant 11β-Hydroxysteroid Dehydrogenase Type I Inhibitors and in Vivo Testing in Diet-Induced Obese Mice

Goldberg, Frederick W., Dossetter, Alexander G., Scott, James S., Robb, Graeme R., Boyd, Scott, Groombridge, Sam D., Kemmitt, Paul D., Sjögren, Tove, Gutierrez, Pablo Morentin, deSchoolmeester, Joanne

Journal:

Journal of Medicinal Chemistry

Year:

2014

Language:

english

File:

PDF, 3.90 MB

english, 2014

8

[Society of Petroleum Engineers European Petroleum Conference - The Hague, Netherlands (1998-10-20)] European Petroleum Conference - A Static Slickline-Retrievable Wellhead Plug System for Use with Horizontal Trees in Offshore Systems

Vick, James, Robb, Ewan, Thomson, David, Collie, Graeme

Language:

english

File:

PDF, 427 KB

english

9

Stimulation of nodal and terminal sprouting of mouse motor nerves by gangliosides

Graeme A. Robb, Roger J. Keynes

Journal:

Year:

1984

Language:

english

File:

PDF, 355 KB

english, 1984

10

Free Ligand 1D NMR Conformational Signatures to Enhance Structure Based Drug Design of a Mcl-1 inhibitor (AZD5991) and other Synthetic Macrocycles

Balazs, Amber Y S, Carbajo, Rodrigo J., Davies, Nichola L, Dong, Yu, Hird, Alexander W, Johannes, Jeffrey W., Lamb, Michelle L, McCoull, William, Raubo, Piotr, Robb, Graeme R., Packer, Martin J, Chiar

Journal:

Journal of Medicinal Chemistry

Year:

2019

Language:

english

File:

PDF, 1.17 MB

english, 2019

11

A chemistry wiki to facilitate and enhance compound design in drug discovery

Robb, Graeme R., McKerrecher, Darren, Newcombe, Nicholas J., Waring, Mike J.

Journal:

Drug Discovery Today

Year:

2013

Language:

english

File:

PDF, 865 KB

english, 2013

12

Improving metabolic stability and removing aldehyde oxidase liability in a 5-azaquinazoline series of IRAK4 inhibitors

Degorce, SÃ©bastien L., Aagaard, Anna, Anjum, Rana, Cumming, Iain A., DiÃ¨ne, Coura R., Fallan, Charlene, Johnson, Tony, Leuchowius, Karl-Johan, Orton, Alexandra L., Pearson, Stuart, Robb, Graeme R.,

Journal:

Bioorganic & Medicinal Chemistry

Year:

2020

File:

PDF, 6.01 MB

2020

13

Matrix-based multiparameter optimisation of glucokinase activators: the discovery of AZD1092

Waring, Michael J., Johnstone, Craig, McKerrecher, Darren, Pike, Kurt G., Robb, Graeme

Journal:

Year:

2011

Language:

english

File:

PDF, 274 KB

english, 2011

14

Discovery of potent, selective small molecule inhibitors of α-subtype of type III phosphatidylinositol-4-kinase (PI4KIIIα)

Raubo, Piotr, Andrews, David M., McKelvie, Jennifer C., Robb, Graeme R., Smith, James M., Swarbrick, Martin E., Waring, Michael J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2015

Language:

english

File:

PDF, 2.78 MB

english, 2015

15

SPIE Proceedings [SPIE Solid State Lasers for Application to Inertial Confinement Fusion (ICF) - Monterey, CA (Tuesday 30 May 1995)] Solid State Lasers for Application to Inertial Confinement Fusion (ICF) - Diffractive optics development for application on high-power solid state lasers

Bett, Thomas H., Stevenson, R. M., Taghizadeh, Mohammad R., Miller, J. M., Lightbody, Malcolm T. M., Blair, Paul, Layet, Ben, Watson, Norman F., Barton, Ian M., Robb, Graeme, McMonagle, J., Andre, Mic

Year:

1995

Language:

english

File:

PDF, 354 KB

english, 1995

16

Learning Medicinal Chemistry Absorption, Distribution, Metabolism, Excretion, and Toxicity (ADMET) Rules from Cross-Company Matched Molecular Pairs Analysis (MMPA)

Kramer, Christian, Ting, Attilla, Zheng, Hao, Hert, Jérôme, Schindler, Torsten, Stahl, Martin, Robb, Graeme, Crawford, James J., Blaney, Jeff, Montague, Shane, Leach, Andrew G., Dossetter, Al G., Grif

Journal:

Journal of Medicinal Chemistry

Year:

2017

Language:

english

File:

PDF, 5.80 MB

english, 2017

17

The discovery of a novel series of glucokinase activators based on a pyrazolopyrimidine scaffold

Bonn, Peter, Brink, D. Mikael, Fägerhag, Jonas, Jurva, Ulrik, Robb, Graeme R., Schnecke, Volker, Svensson Henriksson, Anette, Waring, Michael J., Westerlund, Christer

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2012

Language:

english

File:

PDF, 1.44 MB

english, 2012

18

[Society of Petroleum Engineers European Petroleum Conference - (1998.10.20-1998.10.22)] Proceedings of European Petroleum Conference - A Static Slickline-Retrievable Wellhead Plug System for Use with Horizontal Trees in Offshore Systems

Vick Jr., James, Robb, Ewan, Thomson, David, Collie, Graeme

Year:

1998

Language:

english

File:

PDF, 427 KB

english, 1998

19

Overcoming retinoic acid receptor-α based testicular toxicity in the optimisation of glucokinase activators

Waring, Michael J., Brogan, Iain J., Coghlan, Matthew, Johnstone, Craig, Jones, Huw B., Leighton, Brendan, McKerrecher, Darren, Pike, Kurt G., Robb, Graeme R.

Journal:

Year:

2011

Language:

english

File:

PDF, 257 KB

english, 2011

20

Design of pyrazolo-pyrimidines as 11β-HSD1 inhibitors through optimisation of molecular electrostatic potential

Robb, Graeme R., Boyd, Scott, Davies, Christopher D., Dossetter, Alexander G., Goldberg, Frederick W., Kemmitt, Paul D., Scott, James S., Swales, John G.

Journal:

Year:

2015

Language:

english

File:

PDF, 2.07 MB

english, 2015

21

Systemic bioactivity of intranasal triamcinolone and mometasone in perennial allergic rhinitis

Daniel K. C. Lee, Fiona M. Robb, Erika J. Sims, Graeme P. Currie, Lesley C. McFarlane, Brian J. Lipworth

Journal:

British Journal of Clinical Pharmacology

Year:

2003

Language:

english

File:

PDF, 80 KB

english, 2003

22

Achieving improved permeability by hydrogen bond donor modulation in a series of MGAT2 inhibitors

Scott, James S., Berry, David J., Brown, Hayley S., Buckett, Linda, Clarke, David S., Goldberg, Kristin, Hudson, Julian A., Leach, Andrew G., MacFaul, Philip A., Raubo, Piotr, Robb, Graeme

Journal:

Year:

2013

Language:

english

File:

PDF, 478 KB

english, 2013

23

In situ neutron diffraction studies of single crystals and powders during microwave irradiationElectronic supplementary information (ESI) available: Crystallographic data (powder and single crystal data) in cif format (CCDC reference numbers 185472???185475). See http://www.rsc.org/suppdata/fd/b2/b203379h/

Harrison, Andrew, Ibberson, Richard, Robb, Graeme, Whittaker, Gavin, Wilson, Chick, Youngson, Douglas

Journal:

Faraday Discussions

Year:

2003

Language:

english

File:

PDF, 475 KB

english, 2003

24

Optimising pharmacokinetics of glucokinase activators with matched triplicate design sets – the discovery of AZD3651 and AZD9485

Waring, Michael J., Bennett, Stuart N. L., Boyd, Scott, Campbell, Leonie, Davies, Robert D. M., Hargreaves, David, MacFaul, Philip, Martin, Nathaniel G., Ogg, Derek J., Robb, Graeme R., Wilkinson, Gar

Journal:

Year:

2013

Language:

english

File:

PDF, 430 KB

english, 2013

To build up a library is to create a life. It’s never just a random collection of books.

— Carlos María Domínguez

Official channel

Z-Library Desktop Launcher

Z-Library Since 2009 support@1delivery.pm

EnglishРусскийEspañolItalianoελληνικάاللغة العربيةBahasa IndonesiaBahasa Malaysiaहिन्दीDeutschFrançaisPortuguêsУкраїнськаPolski中文繁體中文日本語Tiếng ViệtAzərbaycan DiliՀայոց լեզուภาษาไทยTürk Diliქართველიবাংলাپښتوతెలుగుاردو한국어SrpskiБългарски